Turing Pharma names chairman to replace Shkreli as CEO

Martin Shkreli, the poster boy for prescription drug price increases who was arrested for securities fraud this week, has stepped down from his post as chief executive officer of Turing Pharmaceuticals Inc, the company said on Friday.

Shkreli was replaced by Turing Chairman Ron Tilles, who said in a statement that the company was committed to continuing to make its flagship drug, Daraprim, which is used to treat an infection called toxoplasmosis in AIDS patients.

SEE MORE: Turing CEO Martin Shkreli arrested in securities fraud probe

Shkreli has become a lightning rod for growing outrage over soaring prescription drug prices after the company acquired Daraprim and raised its price to $750 a tablet from $13.50.

Turing is the only manufacturer of Daraprim.

Shkreli has been under investigation for securities fraud related to hedge fund MSMB Capital Management and biopharmaceutical company Retrophin Inc. He was charged in Brooklyn, New York, on Thursday in a federal indictment.

In October 2014, Shkreli was ousted from Retrophin, which he had founded. The drugmaker sued him for $65 million, saying he had breached his duty to the company.

In recent months, Shkreli has made controversial remarks in the press about raising drug prices and taunted detractors, including Democratic presidential candidate Bernie Sanders, on social media outlets.

Shkreli is also CEO of drugmaker KaloBios Pharmaceuticals Inc. KaloBios, which had planned to shut down operations, named him to that post on Nov. 20 after he and a consortium of investors bought about 70 percent of its outstanding shares.

Nasdaq has placed KaloBios’ stock on a trading halt until the company provides more information.

On Thursday night, Shkreli, who was released on a $5 million bond earlier in the day, tweeted “Glad to be home. Thanks for the support.”


9 Healthy Reasons to Indulge Your Coffee Cravings

There’s no need to feel guilty about your morning cup o’ joe. On the contrary: People who drink four or more cups of coffee a day have up to a 20 percent lower risk of melanoma than those who sip the dark stuff less often, according to a 2015 study in the Journal of the National Cancer Institute.

But this study is hardly the first one touting good news for java junkies. “Coffee is incredibly rich in antioxidants, which are responsible for many of its health benefits,” says Joy Bauer, RD, nutrition and health expert for Everyday Health and The Today Show. And studies show that its caffeine content may also play a protective role in some health conditions.

Beyond lowering your skin cancer risk, you may be surprised to learn that coffee can also decrease your odds of developing the following health issues:

1. Stroke. People who consumed higher amounts of coffee (and/or green tea) each day showed a lower risk of stroke when compared to those who rarely consumed the beverages, according to a 2013 study published in the journal Stroke.

2. Diabetes. People who increased their coffee consumption by more than one cup per day over a four-year period had an 11 percent lower risk of type 2 diabetes over the following four years compared to those who did not change their intake, according to a 2014 study led by Harvard School of Public Health. The researchers also found that decreasing coffee intake by more than a cup per day resulted in a 17 percent higher risk of type 2 diabetes.

3. Stress. Does the smell of a rich French roast seem to wake you up on a sluggish morning? Turns out the aroma may help minimize the effects of sleep deprivation on your body. A 2008 study published in the Journal Agricultural and Food Chemistry found that when stressed-out, sleep-deprived rats simply smelled coffee, they experienced a trigger in gene activity known to protect nerve cells from stress-related damage.

4. Tooth decay. Although sipping a cup of java doesn’t mean you can ditch the floss, coffee may help boost your dental health. A 2009 study published in the Journal of Conservative Dentistry found that black coffee can help prevent tooth decay — the scientists behind the study advised that additives like milk and sugar have a counterproductive effect.

5. Parkinson’s disease. If Parkinson’s disease runs in your family, here’s some promising news: A 2007 study conducted on people with a family history found that those who drank coffee were less likely to develop the debilitating neurological disease than those who didn’t drink the brew. A 2000 study published in Journal of the American Medical Association also demonstrated the protective effects of caffeine without a family history as well: This research revealed a significantly lower occurrence of Parkinson’s disease among participants with higher coffee and caffeine intake.

6. Breast cancer. Women who drank boiled Scandinavian coffee, which is similar to stronger French press, Turkish, or Greek varieties, more than four times a day had a reduced risk of breast cancer when compared to women who drank it less than once a day, according to a 2010 study published in the journal Cancer Causes & Control.

An important note: Because the coffee wasn’t filtered, it contained up to 80 times as many coffee-specific fatty acids, which have been linked to slower growth of cancerous cells.

7. Heart disease. Drinking 3 to 4 cups of coffee per day can lower your risk of developing clogged arteries, an indicator of heart disease, according to a March 2015 study published in the journal Heart. A 2006 study published in The American Journal of Clinical Nutrition, which tracked 27,000 women for 15 years, also found that post-menopausal women who drank 1 to 3 cups of coffee per day lowered their risk of death from cardiovascular disease and other inflammatory diseases.

8. Throat and mouth cancers. Although the research on coffee’s cancer-fighting properties has been mixed, a 2012 study published in the American Journal of Epidemiology found that the caffeinated kind may guard against death from throat and mouth cancers. Compared with coffee abstainers, those who drank more than four cups daily had about half the risk of death from certain mouth and throat cancers.

One coffee caveat: Most health experts agree it’s wise to limit your intake to a few cups a day — that’s a standard 8-ounce mug, not the super-sized beverages many coffee shops offer. Overdoing it can lead to interrupted sleep or insomnia, stomachaches, a racing heart, nervousness, irritability, and nausea. Remember, we’re talking coffee with a splash of milk — not loaded with whipped cream and sugary syrups. “Adding a lot of calories to your coffee can actually raise your risk for diseases like stroke and diabetes,” says Keri Gans, RD, a nutritionist in private practice in New York City.

Also, doctors recommend that pregnant women or people with certain health issues, such as high blood pressure or high blood sugar, limit their caffeine intake. Talk to your doctor if you’re concerned about how much coffee is safe for you.